Engauge digitizer for speakers software#

TIGIT expression was associated with OS and PFS in patients with solid tumors. Funnel plots suggested no publication bias for OS ( P = 0.902), and Egger's test supported this conclusion ( P = 0.537). In addition to cancer type, expression location, sample size, and different statistical analysis methods are also considered the possible causes of heterogeneity between studies. We performed subgroup analysis to explore the source of heterogeneity, colorectal cancer (HR = 2.07, 95% CI, P = 0.518), lung cancer (HR = 1.29, 95% CI, P = 0.094), esophageal cancer (HR = 1.70, 95% CI, P = 0.003), and other cancers (HR = 1.83, 95% CI, P = 0.002).

High expression of TIGIT was a risk factor for overall survival (OS) and progression-free survival (PFS) (HR = 1.44, 95% CI, P = 0.01). Increased expression of TIGIT was associated with poor prognosis. Our literature search identified eight papers comprising 1426 patients with solid tumors.

Engauge digitizer for speakers software#

The Newcastle-Ottawa Scale (NOS) was used to evaluate the quality of the literature, and Stata 16.0 and Engauge Digitizer 4.1 software were used for data analysis. We performed an online search of PubMed, Embase, Web of Science (WOS), and MEDLINE databases for literature published till March 31, 2021. To fully comprehend the role of TIGIT on the prognosis of patients with solid tumors, we conducted a meta-analysis. The expression levels of TIGIT affect the prognosis of patients with solid tumors. T cell immunoglobulin and ITIM domain (TIGIT) is a recently identified immunosuppressive receptor.